Liquid biopsy · curated MDI catalog

Liquid biopsy cancer tests

Liquid biopsy measures molecular signals in blood or other body fluids. The same sample type can be used for very different purposes, including screening, genomic profiling and MRD monitoring.

122 curated profiles currently match this page. MDI lists them alphabetically and does not rank tests by isolated performance numbers, evidence counts, price or popularity.

  • 4Kscore Test — Serum or plasma multi-analyte kallikrein test with an algorithmic score used to aid prostate-biopsy decisions and detection of aggressive prostate cancer.
  • Abbott RealTime IDH1 — U.S. real-time PCR assay for source-scoped IDH1 mutation testing in AML and myeloid malignancy treatment-selection contexts.
  • Abbott RealTime IDH2 — U.S. real-time PCR assay for source-scoped IDH2 mutation testing in acute myeloid leukemia.
  • AlphaLiquid 100 — 118-gene blood-based targeted comprehensive genomic profiling assay for solid tumors.
  • AlphaLiquid HRR — Blood-based targeted NGS assay for homologous-recombination-repair genomic profiling in solid tumors.
  • Avantect Ovarian Cancer Test — Cell-free DNA blood LDT intended as an aid to earlier ovarian-cancer detection in women at elevated risk.
  • Avantect Pancreatic Cancer Test — Blood-based multi-analyte, multiomic test intended to support earlier pancreatic cancer detection in elevated-risk patients.
  • Blueprint Genetics Comprehensive Hereditary Cancer Panel — 160-gene germline panel for inherited cancer susceptibility, including selected non-coding variants.
  • BRACAnalysis CDx — Germline BRCA1/2 companion diagnostic used for treatment selection across specified BRCA-associated cancer indications.
  • BRCAplus — Guideline-based germline hereditary breast cancer panel.
  • CanCatch Custom — Tumor-informed personalized ctDNA MRD approach using WES baseline profiling and patient-specific mutation tracking.
  • CancerDetect — Tissue-informed personalized molecular residual disease and recurrence-monitoring assay for solid tumors.
  • CancerFind — Blood-based multi-cancer early detection assay using methylation, copy-number and fragmentomic features.
  • Cancerguard — Multi-cancer early detection laboratory-developed test for adults 50–84; breast/prostate screening and precancer detection are outside the documented current use.
  • CancerNext — Guideline-based germline hereditary cancer panel.
  • CancerNext-Expanded — Germline hereditary-cancer panel; current vendor page reports 78 genes while recent official 77-gene materials require explicit version separation.
  • CancerPrecision — Tumor-normal targeted sequencing service for comprehensive molecular profiling of solid tumors.
  • CancerVision — Tumor-normal whole-genome sequencing service for comprehensive genomic profiling of solid tumors, with a plasma-based alternative when clinically applicable.
  • CancerVista — ctDNA liquid-biopsy in-house IVD for MRD detection, recurrence surveillance and therapy monitoring across solid tumors.
  • CanScan — Blood-based multi-cancer early detection test using low-depth WGS and AI integration of fragmentomic, genomic and inferred epigenomic cfDNA features.
  • Caris Assure — Whole-blood comprehensive molecular profiling for advanced solid tumors.
  • Caris ChromoSeq — Whole-genome/transcriptome profiling for diagnosed or suspected myeloid malignancies.
  • Caris Detect — Blood-based multi-cancer early detection LDT using whole-genome and whole-transcriptome sequencing with AI.
  • CeGaT Hereditary Tumor Syndromes — Germline hereditary tumor-syndrome testing based on CeGaT ExomeXtra with regularly updated cancer-predisposition gene sets.
  • clonoSEQ — NGS-based clonotype assay for measurable/minimal residual disease assessment in lymphoid malignancies, with disease- and specimen-specific FDA-cleared contexts and additional LDT uses.
  • cobas EGFR Mutation Test v2 — FDA-approved real-time PCR EGFR companion diagnostic for NSCLC.
  • ColoHealth — Blood-based methylated SEPT9 colorectal cancer testing family; current ColoHealth Direct LDT and historical FDA device lineage are modeled separately.
  • Color Hereditary Cancer Genetic Test — Current 29-gene germline hereditary cancer susceptibility test offered through Color Health.
  • ColoScape — Multiplex plasma cfDNA mutation-and-methylation assay used in colorectal cancer screening-triage and diagnostic-aid contexts.
  • COLOTECT CRC Screening — Stool-based colorectal cancer screening test combining DNA methylation and fecal occult blood detection in the current 3.0 configuration.
  • EasyM — Blood-based multiple myeloma MRD monitoring test using clonotypic peptide mass spectrometry to track M-protein.
  • Empower Hereditary Cancer Test — Germline multigene hereditary-cancer test using blood or saliva to assess inherited cancer risk.
  • EPISEEK — Blood-based multi-cancer early detection LDT analyzing abnormal DNA methylation signals associated with more than 60 cancer types.
  • EpiSwitch PSE — Blood-based 3D-genomics test used with PSA to assess current likelihood of prostate cancer.
  • FirstLook Lung — Blood-based cfDNA fragmentomics laboratory-developed test used as an adjunct in the lung-cancer screening pathway; not a replacement for LDCT.
  • Foresight CLARITY — Ultra-sensitive ctDNA molecular residual disease assay using PhasED-Seq phased-variant detection, with strong current use in B-cell lymphoma clinical programs.
  • FoundationOne Germline — 50-gene germline hereditary-cancer panel for inherited cancer susceptibility across multiple hereditary cancer syndromes.
  • FoundationOne Germline More — 154-gene expanded germline hereditary-cancer panel for inherited cancer susceptibility.
  • FoundationOne Heme — DNA/RNA comprehensive genomic profiling LDT for hematologic neoplasms and other source-defined indications.
  • FoundationOne Liquid CDx — Blood-based 324-gene comprehensive genomic profiling and companion-diagnostic test for advanced solid tumors. Regulatory claims are PMA-, supplement-, biomarker-, therapy- and indication-scoped.
  • FoundationOne MRD — Tissue-informed ctDNA MRD assay for stage II-III breast cancer using tumor WGS and multiplex dPCR.
  • FoundationOne Tracker — Tissue-informed circulating-tumor-DNA test for treatment-response monitoring in advanced solid tumors.
  • Galleri — Prescription-only multi-cancer early detection test.
  • GASTROClear — Blood-based miRNA test for early detection of gastric cancer.
  • GeneDx Comprehensive Common Cancer Panel — 49-gene germline hereditary-cancer panel (test code B275) using sequencing and deletion/duplication analysis.
  • GenMineTOP Cancer Genome Profiling System — Japanese tumor-normal DNA/RNA comprehensive genomic profiling system for solid tumors.
  • Guardant Reveal — Tissue-free ctDNA MRD/recurrence and therapy-response monitoring test with current methylation-focused commercial lineage.
  • Guardant360 Liquid CDx — Plasma cfDNA comprehensive genomic profiling and indication-specific companion diagnostic.
  • Haystack MRD — Tumor-informed ctDNA molecular residual disease assay for solid tumors using WES-derived personalized panels tracking up to 50 variants.
  • Invitae Common Hereditary Cancers Panel — NGS germline panel for common hereditary cancer predisposition.
  • Invitae Hereditary Breast and Gyn Cancers Panel — NGS germline panel for hereditary breast and gynecologic cancer predisposition.
  • Invitae Hereditary Breast Cancer STAT Panel — Time-sensitive germline hereditary breast-cancer STAT panel, Labcorp test 898053.
  • Invitae Hereditary Colorectal Cancer Guidelines-based Panel — NGS germline panel for hereditary colorectal cancer predisposition.
  • Invitae Hereditary Pancreatic Cancer Panel — NGS germline panel for hereditary pancreatic cancer predisposition.
  • Invitae Hereditary Prostate Cancer Panel — NGS germline panel for hereditary prostate cancer predisposition.
  • Invitae Multi-Cancer Panel — Current Labcorp Invitae germline multi-cancer hereditary-susceptibility panel, test 898041.
  • Invitae Personalized Cancer Monitoring — Tumor-informed personalized ctDNA monitoring assay for solid tumors.
  • ipsogen BCR-ABL1 mbcr Kit CE — CE-IVD real-time PCR kit for p190 BCR-ABL1 transcript quantification in B-cell acute lymphoblastic leukemia.
  • ipsogen BCR-ABL1 Mbcr Kit CE — CE-IVD real-time PCR kit for p210 BCR-ABL1 transcript quantification in hematologic malignancies.
  • ipsogen JAK2 RGQ PCR Kit — Real-time PCR assay detecting JAK2 V617F in whole blood as an adjunct in evaluation of suspected myeloproliferative neoplasms.
  • K-4CARE — Integrated genomic and transcriptomic profiling with ctDNA MRD monitoring for precision oncology.
  • Labcorp Plasma Complete — 521-gene plasma comprehensive genomic profiling LDT for advanced or metastatic solid tumors.
  • Labcorp Plasma Detect Genome MRD — Tumor-informed whole-genome sequencing ctDNA MRD test currently offered for stage III colon cancer baseline and monitoring.
  • LeukoStrat CDx FLT3 Mutation Assay — PCR and capillary-electrophoresis companion diagnostic for FLT3 ITD and TKD mutations in acute myeloid leukemia.
  • LiquidHALLMARK — Prescription plasma liquid-biopsy assay detecting ctDNA and ctRNA for molecular profiling and treatment selection in advanced cancer.
  • LucenceINSIGHT — Prescription blood-based multi-cancer early detection family using ctDNA and viral DNA with machine-learning tissue localization.
  • LUNGClear — Blood-based miRNA test for early detection of lung cancer.
  • LymphoVista — ctDNA sequencing in-house IVD for lymphoma genotyping, MRD assessment and longitudinal monitoring.
  • MRDVision — Tumor-informed whole-genome MRD assay using a baseline tumor/normal genome and serial blood-based ctDNA monitoring.
  • MSK-ACCESS — Institutional ultra-deep cfDNA sequencing assay for noninvasive genomic profiling and disease monitoring; current panel covers 146 genes.
  • MSK-IMPACT — Tumor-normal targeted DNA sequencing for comprehensive tumor profiling.
  • MyRisk — Germline hereditary-cancer panel; current documented configuration contains 63 clinically recommended genes and must not inherit analytical metrics from historical 25-gene validation.
  • NavDx — Blood-based TTMV-HPV DNA laboratory-developed test used in HPV-driven cancer management and post-treatment recurrence surveillance.
  • Neo Comprehensive - Myeloid Disorders — 164-gene DNA/RNA clinical assay for molecular evaluation of myeloid neoplasms.
  • NEO PanTracer LBx — 514-gene ctDNA liquid-biopsy comprehensive genomic profiling assay for advanced pan-solid tumors, including MSI-H and bTMB.
  • NeXT Personal Dx — Tumor-informed personalized ctDNA LDT using WGS-derived patient-specific signatures for MRD, recurrence and treatment-response monitoring.
  • Nodify CDT — Blood autoantibody classifier that raises malignancy risk for selected pulmonary nodules.
  • Nodify XL2 — Blood-based proteomic classifier to identify lung nodules likely benign.
  • Northstar Response — Tissue-free methylated-ctDNA liquid biopsy for quantitative treatment-response monitoring across advanced solid tumors.
  • Northstar Select — 102-gene plasma ctDNA comprehensive genomic profiling assay for therapy selection in advanced solid tumors.
  • OncoBEAM RAS CRC Kit CE-IVD — CE-IVD plasma ctDNA assay for detection of KRAS and NRAS mutations in colorectal cancer using BEAMing technology.
  • Oncodetect MRD — Tumor-informed ctDNA molecular residual disease test used across solid tumors; current commercial configuration tracks up to 200 tumor-specific variants.
  • OncoExTra — Whole-exome and whole-transcriptome tumor profiling with matched-normal subtraction for advanced solid tumors.
  • Oncoguard Liver — Blood-based aid for HCC detection in an at-risk surveillance population.
  • OncoGuide NCC Oncopanel System — Japanese tumor-normal comprehensive genomic profiling system for solid tumors, with current Version 3 coverage of 124 cancer-related genes and a biliary companion-diagnostic function.
  • OncoGuide PlasmaSeq Oncopanel System — Plasma ctDNA targeted sequencing assay for RAS and BRAF V600E alterations used to support treatment selection in colorectal cancer in Japan.
  • OncoSeek — Blood-based multi-cancer diagnostic-aid test combining seven protein tumor markers with age and sex in an AI model that reports cancer probability and likely tissue of origin.
  • OneTest for Cancer — Blood-based multi-cancer early detection LDT combining multiple serum tumor biomarkers with a machine-learning risk algorithm.
  • OverC Multi-Cancer Detection — Blood-based cfDNA methylation multi-cancer early detection test with six-cancer current product scope; jurisdiction-specific regulatory status.
  • PanTum Detect — Whole-blood multi-cancer screening aid detecting Apo10/DNaseX and TKTL1 signals in monocytes using EDIM/flow-cytometry-based methodology.
  • PGDx elio plasma focus Dx — FDA-authorized plasma cfDNA next-generation sequencing tumor-profiling test for patients already diagnosed with solid malignant neoplasms.
  • Precise MRD — Tumor-informed whole-genome sequencing MRD assay tracking up to 1,000 patient-specific variants for treatment and recurrence monitoring.
  • PredicineCARE — CLIA-certified 200-gene cfDNA assay for treatment selection and comprehensive molecular profiling in solid tumors.
  • ProVue Lung — Proteomics-based blood LDT designed to complement LDCT lung-cancer screening in high-risk adults.
  • QuantideX qPCR BCR-ABL IS Kit — RT-qPCR BCR-ABL1 monitoring kit standardized to the International Scale for chronic myeloid leukemia treatment-response assessment.
  • Quest Comprehensive Hereditary Cancer Panel — 66-gene germline panel for broad hereditary cancer susceptibility, Quest test code 38600.
  • Quest Guideline-Based Hereditary Cancer Panel — 32-gene germline hereditary cancer panel, Quest test code 38611.
  • Quest Hereditary Breast Cancer Panel — 18-gene germline panel for hereditary breast-cancer susceptibility, Quest test code 38621.
  • Quest Hereditary Colorectal Cancer Panel — 20-gene germline panel for hereditary colorectal-cancer susceptibility, Quest test code 38631.
  • RaDaR ST — Personalized tumor-informed ctDNA MRD assay for solid tumors; current ST generation uses WES tumor profiling and tracks up to 48 patient-specific mutations.
  • RadTox — Clinical cfDNA-concentration assay for treatment-response and progression monitoring in solid tumors.
  • Shield — Blood-based colorectal cancer screening test.
  • Signatera — Personalized tumor-informed circulating tumor DNA molecular residual disease test family. Includes the FDA-authorized Signatera CDx MIBC companion-diagnostic configuration and broader laboratory-developed clinical uses that remain separately scoped.
  • SimpleScreen CRC — FDA-approved blood-based colorectal cancer screening test for average-risk adults age 45 and older.
  • SimpleScreen Lung — Blood-based multiomic LDT intended to increase lung-cancer screening participation among eligible high-risk adults not completing LDCT.
  • SPOT-MAS 10 — Blood-based multi-cancer screening test using cfDNA methylation and fragmentomic signals with machine learning.
  • SPOT-MAS CRC — Plasma SEPTIN9 DNA methylation test for colorectal cancer early detection.
  • SPOT-MAS Lung — Plasma multi-omic cfDNA test for early detection of lung cancer.
  • Stockholm3 — Blood-based prostate cancer risk test integrating PSA, additional proteins, a polygenic risk score and clinical variables.
  • Tempus DPYD — Single-gene germline pharmacogenomic test for DPYD-associated fluoropyrimidine toxicity risk.
  • Tempus UGT1A1 — Single-gene germline pharmacogenomic test for UGT1A1-associated anticancer-therapy toxicity risk.
  • Tempus xF — 105-gene plasma liquid-biopsy genomic profiling test for solid tumors.
  • Tempus xF+ — 523-gene plasma liquid-biopsy comprehensive genomic profiling assay for therapy selection and molecular profiling in advanced cancer.
  • Tempus xM — Tumor-naive liquid-only MRD assay combining methylation- and variant-based workflows for stage II-III colorectal cancer.
  • Tempus xR — Whole-transcriptome RNA sequencing test for solid tumors and hematologic neoplasms.
  • Tempus xT CDx — 648-gene tissue comprehensive genomic profiling companion diagnostic.
  • Tempus xT Heme — 648-gene DNA sequencing configuration for hematologic neoplasms.
  • therascreen PIK3CA RGQ PCR Kit — FDA-approved real-time PCR PIK3CA companion diagnostic for breast cancer.
  • Trucheck Intelli — Blood-based multi-cancer early detection test that detects circulating tumor cells and reports likely tissue/tumor context across many solid tumors.
  • Vysis CLL FISH Probe Kit — U.S. peripheral-blood FISH assay for prognostic and source-scoped therapy-selection contexts in chronic lymphocytic leukemia.
  • Xpert BCR-ABL Ultra — Automated quantitative molecular test for BCR::ABL1 major-breakpoint transcripts used for chronic myeloid leukemia monitoring.
  • Xpert NPM1 Mutation — Automated RT-qPCR assay for quantitative monitoring of NPM1-mutated acute myeloid leukemia in CE-IVD markets.

How to interpret these records

Clinical purpose comes first. Historical evidence remains attached to the assay version that was actually studied. Evidence counts describe curation coverage, not test quality. Commercial availability is separate from authorization, reimbursement, eligibility and appropriate use.

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